Studies now suggests that taking a nicotinamide supplement is a very good idea for women attempting pregnancy at advanced maternal age (over 35 years).
Further evidence has been published documenting a role for nicotinamide adenine dinucleotide, otherwise known as NAD+, an activated B group vitamin, that acts in oocyte health, especially in older women. As eggs mature, increased levels of NAD+ help ensure they can retain the bulk of their cellular building blocks.
Egg quality decline is a concern for all women as we age, and it seems anything we can do to support the oocyte has the potential to improve IVF outcomes. This may especially be the case for women on the cusp of needing to make the challenging decision to abandon fertility treatment or pivot to IVF using donor eggs.
My patients using my personally formulated supplements will be happy to know that they have been taking nicotinamide already.
Vegemite is a great B vitamin supplement many of my patients are familiar with. It seems we Aussies have been long ahead of the game.
